High School Science: Common Core State Standards and Support Materials: Living Environment

From the dynamic thinker routinely compared to Malcolm Gladwell, E. O. Wilson, and James Gleick, The Ghost Map is a riveting page-turner with a real-life historical hero that brilliantly illuminates the intertwined histories of the spread of viruses, rise of cities, and the nature of scientific inquiry. These are topics that have long obsessed Steven Johnson, and The Ghost Map is a true triumph of the kind of multidisciplinary thinking for which he's become famous-a book that, like the work of Jared Diamond, presents both vivid history and a powerful and provocative explanation of what it means for the world we live in. The Ghost Map takes place in the summer of 1854. A devastating cholera outbreak seizes London just as it is emerging as a modern city: more than 2 million people packed into a ten-mile circumference, a hub of travel and commerce, teeming with people from all over the world, continually pushing the limits of infrastructure that's outdated as soon as it's updated. Dr. John Snow-whose ideas about contagion had been dismissed by the scientific community-is spurred to intense action when the people in his neighborhood begin dying. With enthralling suspense, Johnson chronicles Snow's day-by-day efforts, as he risks his own life to prove how the epidemic is being spread. When he creates the map that traces the pattern of outbreak back to its source, Dr. Snow didn't just solve the most pressing medical riddle of his time. He ultimately established a precedent for the way modern city-dwellers, city planners, physicians, and public officials think about the spread of disease and the development of the modern urban environment. The Ghost Map is an endlessly compelling and utterly gripping account of that London summer of 1854, from the microbial level to the macrourban-theory level-including, most important, the human level. Watch a QuickTime trailer for this book.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vacci≠ uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia—a land of wooden slave quarters, faith healings, and voodoo—to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?             Intimate in feeling, astonishing in scope, and impossible to put down,The Immortal Life of Henrietta Lackscaptures the beauty and drama of scientific discovery, as well as its human consequences.